使用加速氦离子的相对生物学效果随肿瘤大小的变化。

Acta radiologica: therapy, physics, biology Pub Date : 1976-06-01 DOI:10.3109/02841867609131960

J Shaeffer, A M El-Mahdi, H Aceto, W C Constable

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引用次数: 3

摘要

加速氦离子束对小鼠骨肉瘤的RBE进行了测定，其大小从单细胞到肉眼可见的约1 × 10(-2) mm3的肺菌落不等。RBE随着肿瘤大小的增加而增加，这为临床试验选择晚期肿瘤病例使用相对高LET辐射源提供了一定的生物学依据。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Variation of the relative biologic effectiveness with tumor size using accelerated helium ions.

The RBE of an accelerated helium ion beam was determined on murine osteosarcomas ranging in size from single cells to visibly detectable lung colonies of approximately 1 X 10(-2) mm3. That the RBE increased as tumor size increased provides some biologic basis for the selection of advanced cases of neoplasia for clinical trials using relatively high LET radiation sources.

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Acta radiologica: therapy, physics, biology

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