高性能、网格和云计算在高通量测序中的作用

2016 IEEE International Conference on Bioinformatics and Biomedicine (BIBM) Pub Date : 2016-12-15 DOI:10.1109/BIBM.2016.7822643

G. Lightbody, Fiona Browne, Huiru Zheng, Valeriia Haberland, J. Blayney

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引用次数: 3

摘要

我们已经进入了全基因组测序的时代，使用高通量测序技术在一天内倾泻千兆字节的读取。为了从如此丰富的数据中充分受益，需要高性能的工具和系统来提取序列中的信息。本文概述了高通量测序的发展以及该领域发展的工具、基础设施和数据管理，以支持个性化医疗的关键领域。论文最后展望了这些技术及其应用的未来，以及它们如何影响临床治理。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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The role of high performance, grid and cloud computing in high-throughput sequencing

We have reached the era of full genome sequencing using high throughput sequencing technologies pouring out gigabases of reads in a day. To fully benefit from such a profusion of data high performance tools and systems are needed to extract the information lying within the sequences. This paper provides an overview of the evolution of high-throughput sequencing and the tools, infrastructure and data management developing in this space to support a key area in personalized medicine. The paper concludes by providing an outlook in the future of such technologies and their applications and how they might shape clinical governance.

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2016 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)

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