埃塞俄比亚南部肯巴塔坦巴罗区公立医院接受抗逆转录病毒治疗的成年人抑郁症患病率及相关因素

Addisu Girma, Wondwosen Tekleselasie, T. Yohannes
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The aim of this study was to assess the prevalence and associated factors of depression among adult people living with HIV attending antiretroviral therapy clinic in public hospitals at KembataTembaro Zone, South Ethiopia,2020.MethodAn institution based cross sectional study was conducted in public Hospitals of KembataTembaro Zone from March 1/2020-April30/2020. Systematic random sampling technique was used to select the study participants. Data were collected using a pretested and structured questionnaire. Multivariable Logistic regression was performed to assess factors associated with depression using odds ratio at 95% confidence interval and P-value < 0.05.ResultsThe prevalence of depression was 44.3% (95% CI: 39.4% − 49.2 Being female (AOR = 2.03, 95% CI: 1.21,3.40), living alone (AOR = 3.09,95%CI :1.68,5.68), Having HIV related stigma (AOR = 2.85, 95% CI: 1.73, 4.71), poor social support (AOR = 2.55, 95% CI: 1.48, 4.78), CD4 count less than 350 cell/ul (AOR = 2.66, 95% CI: 1.48, 4.58) and Poor medication adherence (AOR = 2.19,95% CI: 1.32, 3.65) were factors significantly associated with depression.ConclusionThe prevalence of depression was high. Being female, living alone, having HIV related stigma, Poor social support, CD4 count less than 350 cell/ul and poor medication adherence were associated with depression. 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引用次数: 1

摘要

目前,使用抗逆转录病毒治疗的人类免疫缺陷病毒感染者的预期寿命更长。然而;抑郁症在这些患者中最为常见,由于治疗依从性降低和医疗结果恶化(包括治疗耐药性),显著导致健康结果不佳,增加了对医疗资源的利用需求,并增加了发病率和死亡率。本研究的目的是评估2020年在南埃塞俄比亚KembataTembaro区公立医院抗逆转录病毒治疗诊所就诊的成年艾滋病毒感染者的抑郁症患病率及其相关因素。方法于2020年3月1日至2020年4月30日在京巴塔区公立医院进行基于机构的横断面研究。采用系统随机抽样方法选择研究对象。使用预先测试和结构化的问卷收集数据。采用多变量Logistic回归评估抑郁症相关因素,比值比为95%置信区间,p值< 0.05。结果女性(AOR = 2.03, 95%CI: 1.21,3.40)、独居(AOR = 3.09,95%CI:1.68,5.68)、HIV相关污名(AOR = 2.85, 95%CI: 1.73, 4.71)、社会支持差(AOR = 2.55, 95%CI: 1.48, 4.78)、CD4细胞计数低于350细胞/ul (AOR = 2.66, 95%CI: 1.48, 4.58)、药物依从性差(AOR = 2.19,95% CI: 1.32, 3.65)是与抑郁症显著相关的因素。结论抑郁症的患病率较高。女性、独居、有与HIV相关的耻辱感、缺乏社会支持、CD4细胞计数低于350 /ul以及药物依从性差与抑郁症相关。抑郁症应作为艾滋病毒患者常规咨询的一部分,以确保早期发现和治疗。
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Prevalence of Depression and Associated Factors among Adults on Antiretroviral Therapy In Public Hospitals of Kembata Tembaro Zone, South Ethiopia
BackgroundCurrently, people living with Human Immunodeficiency Virus have longer life expectancies with the use of antiretroviral therapy. However; depression is the most common in these patients, which has markedly resulted to poor health outcomes due to reduced adherence to treatment and deterioration of medical outcomes, including treatment resistance, increase the demand for the utilization of medical resources and increase the morbidity and mortality. The aim of this study was to assess the prevalence and associated factors of depression among adult people living with HIV attending antiretroviral therapy clinic in public hospitals at KembataTembaro Zone, South Ethiopia,2020.MethodAn institution based cross sectional study was conducted in public Hospitals of KembataTembaro Zone from March 1/2020-April30/2020. Systematic random sampling technique was used to select the study participants. Data were collected using a pretested and structured questionnaire. Multivariable Logistic regression was performed to assess factors associated with depression using odds ratio at 95% confidence interval and P-value < 0.05.ResultsThe prevalence of depression was 44.3% (95% CI: 39.4% − 49.2 Being female (AOR = 2.03, 95% CI: 1.21,3.40), living alone (AOR = 3.09,95%CI :1.68,5.68), Having HIV related stigma (AOR = 2.85, 95% CI: 1.73, 4.71), poor social support (AOR = 2.55, 95% CI: 1.48, 4.78), CD4 count less than 350 cell/ul (AOR = 2.66, 95% CI: 1.48, 4.58) and Poor medication adherence (AOR = 2.19,95% CI: 1.32, 3.65) were factors significantly associated with depression.ConclusionThe prevalence of depression was high. Being female, living alone, having HIV related stigma, Poor social support, CD4 count less than 350 cell/ul and poor medication adherence were associated with depression. Depression should be included as part of the routine consultation of HIV patients to ensure early detection and treatment.
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