无泵体外肺辅助

A. Phillipp, R. Behr, MOt M. Rengr, Moo D M. Kaiser, Mdo Birnbaum, Abt. Kardiotechnik
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引用次数: 13

摘要

体外肺辅助(ECLA)是治疗急性肺功能不全的一种既定形式。传统的方式是静脉-静脉旁路。股静脉和锁骨下静脉是首选的插管部位。血液是用滚轴泵或离心泵泵送的。有时使用肝素涂层套管、膜氧合器(MO)和导管,这可以显著降低出血的风险。然而,每分钟泵送1.0至4.0升的装置表明细胞血液成分存在持续的机械应力,并导致一定程度的溶血。一名42岁的急性胰腺炎患者和边缘凝血参数发展为深度肺功能不全。所有的机械通气方式都用尽了,而且证明是不够的。在血流动力学良好的情况下,进行了为期10天的动静脉无泵ECLA,此时患者可以成功断奶。膜式氧合器通过股动脉和股静脉插管连接。
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Pumpless Extracorporeal Lung Assist
Extracorporeallung assist (ECLA) is an established form of treatment for acute pulmonary insufficiency. Classically, it takes the form of veno-venous bypass. The femoral vein and the subclavian vein are favored cannulation sites. Blood is pumped with either a roller or a centrifugal pump. Sometimes heparin-coated cannulae, membrane oxygenators (MO), and tubing are used, which may significantly reduce the risk of bleeding. A device pumping 1.0 to 4.0 liters per minute nevertheless signifies a persistent mechanical stress for the cellular blood components and causes some degree of hemolysis. A 42 year old patient with acute pancreatitis and marginal clotting parameters developed profound pulmonary insufficiency. All modes of mechanical ventilation were exhausted and proved to be inadequate. Under good hemodynamic conditions, an arterio-venous pumpless ECLA was instituted for a duration of 10 days, when the patient could be successfully weaned. The membrane oxygenator was connected via cannulae in the femoral artery and femoral vein.
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