热响应凝胶探针对球体的微组装

Masaru Takeuchi, M. Nakajima, T. Fukuda, Y. Hasegawa
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引用次数: 0

摘要

本文通过对细胞球体的操纵来构建组织工程应用的三维细胞结构。用热反应凝胶处理球体,并检查细胞活力。经过处理的细胞存活率超过90%。结果表明,这些球体可以在热响应聚合物溶液中组装,在保持其生存条件的情况下构建三维体外细胞体系。
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Microassembly of spheroids by thermoresponsive gel probe
In this paper, manipulation of cell spheroids was conducted to construct 3D cell structures for tissue engineering applications. The spheroids were manipulated using thermoresposnive gel, and the cell viability was checked. The manipulated cells show more than 90 % viability. The results indicate that the spheroids can be assembled inside thermoresponsive polymer solution to construct 3D in vitro cell systems with keeping their live conditions.
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