蜂胶蒸压处理同种异体骨移植物骨传导和骨诱导的影像学监测

B. Abdellatif, Hamdi Mohamed, Amara Karim, B. Asma
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引用次数: 3

摘要

兽医骨科医师经常面临长骨骨干区骨物质流失的问题。我们的研究是基于一种生物方法,通过在全身麻醉和无菌条件下在股骨干中植入一厘米长的高压灭菌的同种异体原位移植物来填补节段性骨丢失。实验涉及8只成年狗,来自当地品种和不同性别;分成两组。将不含蜂胶的同种异体热压灭菌移植物植入第一动物组(对照组),然后将相同的移植物植入第二动物组。我们研究的目的是确定蜂胶覆盖的骨诱导和骨导电性同种异体移植物,并在临床和影像学上跟踪高压灭菌移植物的结合。结果表明,使用蜂胶覆盖的移植物加速了骨诱导和骨传导过程,这反映在愈伤组织的早期传代。在高压灭菌的同种异体移植物上使用一层薄薄的蜂胶,刺激周围和脊柱骨诱导,并加速近端和远端界面的骨整合,这种现象可以根据移植物上蜂胶的用量来控制。
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Radiography Monitoring of Osteoconduction and Osteoinduction of Orthotopic Allograft Autoclaved Covered With Propolis
The veterinarian orthopedic surgeon is often faced to the loss of bone substance in diaphyseal region of long bones. Our study is based on a biological approach to the filling of segmental bone loss by implanting an autoclaved orthotopic allograft of one centimeter length covered and uncovered with propolis in the femoral diaphysis under general anesthesia and sterile condition. The experiment involved eight adult dogs, from local breed and different sex; split into two groups. An autoclaved allograft without propolis was implanted for the first animals group (control group ) then the same graft has been implanted to the second animals group. The aim of our study is to determine the osteoinductive and osteoconductive allograft covered with propolis, to follow clinically and radiologically the incorporation of the autoclaved graft.The results showed that the use of a graft covered with propolis accelerated the osteoinductive and osteoconductive process, this is reflected by an early passage of the callus . The use of a thin layer of propolis on a autoclaved allograft, stimulated peripheral and spinal osteoinduction, and accelerated osseointegration at both proximal and distal interfaces, this phenomenon can be controlled depending on the amount used of propolis on the graft.
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