COVID-19凝血病患者的围手术期管理

S. Oriol-López
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摘要

. 2019年底在中国出现的SARS-CoV-2冠状病毒疾病已迅速传播成为大流行,其临床特征从无症状到严重形式,其中患者出现凝血异常,通常为高凝状态,可能演变为弥散性血管内凝血,多器官衰竭和/或死亡。重要的是调查合并症;从第一次接触开始验证凝血状态,分析途径:内源性、外源性、共同、纤溶系统和血小板计数,使用血栓弹性成像和超声心动图等技术。使用抗凝剂有指征时,可使用未分级或低分子量肝素,配合实验室试验调整剂量,以避免低凝状态,必要时使用血液制品。记住,抗病毒治疗可能与抗凝剂相互作用,尤其是口服抗凝剂,出血并不常见。安装的导管存在闭塞问题,必须避免频繁使用肝素清洗。如果患者需要紧急手术或侵入性手术,必须验证凝血的演变,如果不能推迟,则根据检测到的改变使用血液制品治疗。遵循手术室管理算法,避免卫生人员感染。
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Manejo perioperatorio del paciente con coagulopatía por COVID-19
. The appearance of the SARS-CoV-2 coronavirus disease, in China late 2019, has spread rapidly to become a pandemic, the clinical characteristics which range from being asymptomatic to having the severe form, where patients present abnormalities of the Coagulation, generally a hypercoagulable state, may evolve to disseminated intravascular coagulation, multiple organ failure, and / or death. It is important to investigate comorbidities; verify the coagulation status from the first contact, analyzing the routes: endogenous, exogenous, common, fibrinolytic system and platelet count, using technology like thromboelastography and sonoclot. The use of anticoagulants is indicated, it can be used unfractionated or low molecular weight heparin, with laboratory tests to adjust the dose, in order to avoid states of hypocoagulability, use blood products when necessary. Remember that antiviral treatment can have interactions with anticoagulants, especially oral ones, bleeding is not common. There are occlusion problems of installed catheters, one must avoid frequent of these washing with heparin. If the patient requires an emergency surgical or invasive procedure, it must verify the evolution of the coagulation, if it cannot be postponed, use treatment with blood products according to the alteration detected. Follow the management algorithm in the operating room to avoid infections from health personnel.
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