疟疾疫苗:一个有新盟友的全球问题

Silvia Pimenta, Paulo Sousa
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摘要

目标:尽管在过去十年中通过若干国家和机构的集体努力实现了各种目标,但疟疾目前仍然是全球影响最大的传染病之一。在这篇综述中,我们打算确定近年来采取的措施的影响,以及COVID-19大流行和疟疾疫苗研究的影响。方法:这是一篇基于国际实体的科学文章和技术指南的科学文献探索性研究的综述。结果:预防和治疗疟疾仍然是降低疟疾死亡率和发病率的最重要措施。COVID-19大流行虽然给诊断、预防和治疗措施的分配带来了新的挑战,但同时也表明,通过集体和有组织的努力,可以取得显着进展。最近推荐的疫苗概述了疟疾的新方向,可能有助于根除疟疾。结论:防治这一疾病还有很长的路要走,但随着全球措施的实施,特别是对最贫穷国家的投资,以及利用疫苗等新工具,有可能实现为今后几十年确定的目标。
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VACINA DA MALÁRIA: UM PROBLEMA GLOBAL COM UMA NOVA ALIADA
OBJECTIVES: Despite the various goals achieved in the last decade, from the collective effort of several countries and institutions, malaria currently remains one of the infectious diseases with the greatest global impact. In this review, we intend to establish the impact of the measures taken in recent years, as well as the effects of the COVID-19 pandemic and the research into vaccines against malaria. METHODS: This is a review by means of an exploratory study of the scientific literature, which was based on scientific articles and technical guides from international entities. RESULTS: The prevention and treatment of malaria continue to be the most important measures to reduce the mortality and morbidity associated with this disease. Although the COVID-19 pandemic has brought new challenges regarding the distribution of measures of diagnosis, prevention, and treatment, at the same time, it has shown that with collective and organized effort, remarkable advances can be achieved. The recently recommended vaccine outlines a new direction for malaria, potentially contributing to its eradication. CONCLUSION: There is still a long way to go in the fight against this disease, but with the implementation of measures globally, in particular investment in the poorest countries, and with the new tools available, such as vaccines, it is possible to achieve the objectives defined for the coming decades.
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