新冠肺炎后合并糖尿病患者动脉高血压病程的特点

O. Voloshyna, V. Zbitneva, E. Zubok, I. Balashova, I. Lysyi, О. Dukova, A. Voloshyn, О. Chekhlova
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引用次数: 1

摘要

介绍。最近的出版物表明,冠状病毒感染住院患者最常见的合并症是动脉高血压(AH)、糖尿病(DM)和冠心病。然而,相关文献对covid -19后患者AH病程的特殊性,特别是合并DM的特殊性报道不足。研究的目的。Тo调查合并糖尿病患者既往感染COVID-19的高血压病程特点。材料和方法。我们研究了48例既往感染Covid-19的II-III期1-3度原发性高血压并伴有糖尿病的患者,年龄52-72岁。结果。据估计,在新冠肺炎复发的高血压患者中,超过1/3的人抱怨经常头痛、心悸、咳嗽、肌肉和关节疼痛、疲劳和睡眠障碍。然而,伴有糖尿病的患者更有可能抱怨全身无力和消化不良。在许多患者中,无论是否伴有病理,在妊娠后期,c反应蛋白升高超过3mg /l,纤维蛋白原水平升高,表明该组患者心血管并发症的风险增加。大多数患者在治疗期间血压控制恶化。不受控制的高血压在治疗急性COVID-19的住院患者中更为常见,无论是否存在糖尿病。结论。与没有糖尿病的AH患者(60.9%)相比,AH合并糖尿病的患者在covid后期间检测到未控制的高血压的频率明显更高(76.0%的病例(p = 0.01))。合并糖尿病患者血压控制恶化在服用三种或三种以上降压药物的患者中更为常见(p值小于0.001),这一概念需要进一步纠正降压治疗。
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Peculiarities of Arterial Hypertension Course in Patients with Concomitant Diabetes Mellitus in the Post-COVID Period
Introduction. Recent publications indicate that the most common comorbidities in hospitalized patients with coronavirus infection were arterial hypertension (AH), diabetes mellitus (DM), and coronary heart disease. However, the peculiarities of AH course in post-COVID-19 patients, especially with concomitant DM, are insufficiently covered in the relevant literature. The aim of the study. Тo investigate the peculiarities of hypertension course in patients with concomitant diabetes mellitus previously affected with COVID-19 infection. Materials and methods. We examined 48 patients with essential hypertension of stage II-III of 1-3 degrees, and concomitant DM, previously affected with Covid-19, 52-72 years of age. Results. It has been estimated that more than 1/3 of patients with hypertension who relapsed to COVID-19 complained of frequent headaches, palpitations, coughs, muscle and joint pain, fatigue and sleep disturbances. However, patients with concomitant DM were significantly more likely to complain of general weakness and indigestion. In many patients, regardless of the presence of concomitant pathology, in the postcocious period there was indicated an increase in C-reactive protein more than 3 mg/l and enhanced fibrinogen levels, indicating an increased risk of cardiovascular complications in this group patients. Most patients experienced worsening of blood pressure control during COVID-19 treatment. Uncontrolled hypertension was significantly more common in patients hospitalized for the treatment of acute COVID-19, regardless of DM presence. Conclusions. In patients with AH and concomitant DM significantly more often (76.0 % of cases (p is equal to 0.01)) – compared to patients with AH without DM (60.9 %) was detected uncontrolled hypertension in the post-COVID period. Worsening of blood pressure control in patients with concomitant DM is significantly more common (p value less than 0.001) in those patients who took three or more antihypertensive drugs, this notion require additional correction of antihypertensive therapy.
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