Influence of Red Blood Cell Distribution Width on Long-term Prognosis of Percutaneous Coronary Intervention for Patients with Non-ST Segment Elevation Acute Coronary Syndrome.

Objective The aim of this study was to investigate the influence of red blood cell distribution width (RDW) on the long-term prognosis of percutaneous coronary interventional (PCI) for patients with non-ST segment elevation acute coronary syndrome (NSTEACS). Methods 2185 NSTEACS cases with coronary artery disease and preoperative record of RDW accepting elective PCI treatment from July 2009 to September 2011 were selected. According to preoperative RDW levels, the patients were divided into two groups. One thousand, one hundred and seventy cases belonged to RDW <12.2 group, 1015 cases belonged to RDW ≥12.2 group. The clinical characteristics and the incidence of postoperative mortality in the two groups were compared. The follow-ups were performed for an average of 540 days. Results Patients in the RDW ≥12.2 group were females with characteristics such as hypertension, history of cerebrovascular disease, hospital application of β-blockers and high BMI in admission, low hemoglobin levels and total cholesterol levels. The postoperative mortality of RDW ≥12.2 group (2.7% vs 1.0%, P=0.004) was significantly higher than that of RDW <12.2 group. In multivariate Cox regression analysis, after adjustment for other factors, RDW ≥12.2 of the patients in postoperative PCI was an independent predicted factor for mortality (HR 2.171, 95% CI 1.007-4.680, P=0.048). Conclusion High RDW in postoperative PCI was an independent predictor factor influencing mortality.