{"title":"纳米粒子在癌症治疗中的应用","authors":"K. Haume","doi":"10.1201/9781351166560-29","DOIUrl":null,"url":null,"abstract":"More than 50% of all cancer patients receive radiotherapy which largely means X-ray therapy. X-rays kill cells by the deposition of energy (the “dose”) into the cells, but unfortunately these X-rays also damage healthy cells. Furthermore, radiation is introduced from many angles to increase the dose on the tumor leading to irradiation of much more healthy tissue than strictly necessary - this can be detrimental, especially for brain tumors (see image). Therefore what is needed is a new therapy that allows more targeted application of the radiation to reduce damage to healthy cells.","PeriodicalId":294696,"journal":{"name":"Rediscovering Cancer: From Mechanism to Therapy","volume":"30 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2015-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Nanoparticles in Cancer Therapy\",\"authors\":\"K. Haume\",\"doi\":\"10.1201/9781351166560-29\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"More than 50% of all cancer patients receive radiotherapy which largely means X-ray therapy. X-rays kill cells by the deposition of energy (the “dose”) into the cells, but unfortunately these X-rays also damage healthy cells. Furthermore, radiation is introduced from many angles to increase the dose on the tumor leading to irradiation of much more healthy tissue than strictly necessary - this can be detrimental, especially for brain tumors (see image). Therefore what is needed is a new therapy that allows more targeted application of the radiation to reduce damage to healthy cells.\",\"PeriodicalId\":294696,\"journal\":{\"name\":\"Rediscovering Cancer: From Mechanism to Therapy\",\"volume\":\"30 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2015-06-09\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Rediscovering Cancer: From Mechanism to Therapy\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1201/9781351166560-29\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Rediscovering Cancer: From Mechanism to Therapy","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1201/9781351166560-29","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
More than 50% of all cancer patients receive radiotherapy which largely means X-ray therapy. X-rays kill cells by the deposition of energy (the “dose”) into the cells, but unfortunately these X-rays also damage healthy cells. Furthermore, radiation is introduced from many angles to increase the dose on the tumor leading to irradiation of much more healthy tissue than strictly necessary - this can be detrimental, especially for brain tumors (see image). Therefore what is needed is a new therapy that allows more targeted application of the radiation to reduce damage to healthy cells.