甲状腺滤泡性癌转移的细胞诊断:附3例报告

T. Santosh, M. Patro, A. Bal, N. Puneeta
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引用次数: 1

摘要

背景:滤泡性甲状腺癌(FTC)通常具有相对良性的临床病程,长期预后良好。最常见的转移部位是肺和骨。细针吸细胞学(FNAC)在转移性FTC的诊断和早期发现中具有重要作用。确定远处转移的存在很重要,因为它是最重要的预后指标(与50%的死亡率相关)。病例史:我们报告了三例在不同部位出现多发性肿胀和骨受累的病例。在所有的三个病例中,细胞学检查显示转移性甲状腺滤泡癌的诊断。结论:转移性FTC的细胞学诊断报道甚少。上皮细胞呈重复性微滤泡型排列有助于诊断转移性FTC。这很重要,因为这直接关系到病人的治疗。因此,病理学家和临床医生都需要对转移性FTC的诊断有更多的认识。
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Cytodiagnosis Of Follicular Carcinoma Thyroid From Metastatic Sites: A report Of Three Cases
Background: Follicular thyroid carcinomas (FTC) usually have a relatively benign clinical course, with good long-term prognosis. The most common sites of metastases are lung and bone. Fine needle aspiration cytology (FNAC) plays an important role in the diagnosis and early detection of metastatic FTC. It is important to identify the presence of distant metastasis as it is the most important prognostic indicator (associated with 50% mortality). Case history: We report three cases who presented with multiple swellings and bony involvement at different sites. In all the three cases, aspiration cytology revealed the diagnosis of metastatic follicular thyroid carcinoma. Conclusion: Cytologic diagnosis of metastatic FTC has been reported rarely. Epithelial cells arranged in repitative microfollicular pattern aids in making the diagnosis of metastatic FTC. It’s significant as this has a direct bearing upon the management of the patient. Hence more awareness is required for both pathologist and clinicians regarding the diagnosis of metastatic FTC.
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