颅神经嵴切除与独眼眼发育。

The South African journal of medical sciences Pub Date : 1975-01-01

M J Toerien

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引用次数: 0

摘要

切除前体细胞到5个体细胞小鸡胚胎的颅神经嵴细胞会产生怪物，这些怪物在所有基本方面都与人类独眼症相同。原发性病变包括对前脑的损伤，从而抑制鼻基板和鼻器官的发育，并破坏前神经嵴细胞，导致鼻和眶间间隔以及面部真皮骨架的缺失。

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Cranial neural crest extirpation and cyclopian development.

Extirpation of cranial neural crest cells in presomite to 5 somite chick embryos produces monsters which in all essential respects are identical to human cyclopias. The primary lesion involves damage to the forebrain and consequently the inhibition of the nasal placode and nasal organ development as well as the destruction of the anterior neural crest cells, with the resultant absence of the nasal and interobital septa and of the facial dermal skeleton.

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The South African journal of medical sciences

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