舌单发鳞状细胞乳头状瘤

T. Aldelaimi, A. Khalil
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摘要

两个月前,一名11岁的孩子到颌面外科就诊,主诉舌头出现无痛病变。此外,他还抱怨口腔异物感。他否认有吸毒史,也没有家族病史。口腔内临床检查显示舌背软而无痛的肿块,有许多指状突起,呈“花椰菜”或疣样外观。(A组)在局部麻醉下,患者接受940 nm二极管激光,3W, CW的手术干预。病变被完全切除后送去做组织病理学检查,结果显示为鳞状乳头状瘤(B组)。鳞状乳头状瘤是层状鳞状上皮的良性增生,导致口内粘膜表面出现疣状或乳头状外生肿块。它主要见于小舌、上颚、嘴唇、颊粘膜和舌头。确切的病因尚不清楚,但它与人类乳头瘤病毒6型和11型有关。口腔鳞状乳头状瘤每250个成年人中就有1个。它占所有儿科口腔病变的7-8%。随访6周(C组),患者完全愈合,功能和美观均良好。
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Lingual Solitary Squamous Cell Papilloma
A n 11-years-old child attended the Department of Maxillofacial Surgery complaining of a painless tongue lesion two months ago. Besides, he was complaining of oral foreign body sensation. He denied a history of taking drugs and no family history of the same problem. Intraoral clinical examination showed soft, non-tender mass over the dorsum of the tongue with numerous finger-like projections that impart a ”cauliflower” or wart-like appearance. (Panel A). Under local anesthesia, the patient underwent surgical intervention using a 940 nm diode laser, 3W, CW. The lesion was completely removed and sent for histopathological examination that revealed squamous papilloma (Panel B). Squamous papilloma is a benign proliferation of the stratified squamous epithelium which results in a verrucous or papillary exophytic mass from the intraoral mucosal surface. Mostly, it is seen at the uvula, palate, lips, buccal mucosa, and tongue. The exact etiology is still unknown, but it is associated with human papillomavirus types 6 and 11. The oral squamous papilloma occurs in 1 of every 250 adults. It comprises 7-8% of all pediatric oral lesions. At 6-weeks follow-up (Panel C), there was complete healing with a good functional and aesthetic outcome.
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