大参数空间下癌症模拟结果的制备、探索和比较

A. Lunzer, R. Belleman, P. Melis, G. Stamatakos
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引用次数: 7

摘要

ACGT Oncosimulator是一种基于网格的综合系统,由欧洲和日本的25个合作伙伴共同开发,用于模拟肿瘤和周围组织对各种治疗形式的反应。模拟代码的验证是一项活动,需要对代码的几十个参数中的每一个参数的影响进行广泛的人工驱动的视觉调查,并将模拟结果与过去患者治疗的已知结果进行比较。因此,这项活动需要一个可视化环境,支持用户处理一个非常大的潜在结果空间,并快速设置可视化,突出显示可用结果的选定子集之间的差异。我们描述了OncoRecipeSheet的创新特性,这是一个为满足这些需求而设计的环境。
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Preparing, Exploring and Comparing Cancer Simulation Results within a Large Parameter Space
The ACGT Oncosimulator is an integrated Grid-based system, under development within a 25-partner European-Japanese project, for patient-specific simulation of the response of a tumour and surrounding tissue to various forms of therapy. The validation of the simulation code is an activity requiring extensive human-driven visual investigation of the influence of each of the dozens of parameters to the code, and comparison of the simulation results against the known outcomes of past patient treatments. This activity therefore calls for a visualisation environment that supports users in working with an extremely large potential result space, and in rapidly setting up visualisations that highlight the differences between chosen subsets of available results. We describe the innovative features of the OncoRecipeSheet, an environment designed to meet these requirements.
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