133Xe在血液和眼组织之间的分配系数。

Nuclear-Medizin Pub Date : 1975-12-15
H Kowalski, A Marczak, A Moszczyńska-Kowalska
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引用次数: 0

摘要

测定了133Xe在体外37℃和不同红细胞压积值条件下对兔玻璃体、结膜和外眼肌的相对溶解度系数和组织-血液分配系数。红细胞压积40的分配系数为:房水0.49 ml/ml,玻璃体0.50 ml/ml,结膜0.81 ml/g,眼外肌0.77 ml/g。结果表明,133Xe在兔红细胞中的溶解度比在人红细胞中的溶解度高50%左右。讨论了这一事实对组织间隙法测量血流精度的影响。
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Partition coefficient of 133Xe between blood and eye tissues.

The relative solubility coefficient of 133Xe and the tissue-blood partition coefficient for the aqueous humour vitreous body, conjunctiva and external eye muscles of the rabbit were determined in vitro at 37 degrees C and at various haematocrit values. The partition coefficient for haematocrit 40 was: for the aqueous humour 0,49 ml/ml, for the vitreous body 0,50 ml/ml, for the conjunctiva 0,81 ml/g and for the external eye muscles 0,77 ml/g. It was found that the solubility of 133Xe in rabbit erythrocytes is about 50 per cent higher than that in human red cells. The consequences of this fact for the precision of blood flow measurements by the method of tissue clearance are discussed.

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