手部巨大脂肪瘤:一种极其罕见的疾病!

Chedi Saadi, Khairi Saibi, Meriem Oumaya, M. Ounaies, Said Baccari, L. Tarhouni
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摘要

脂肪瘤是最常见的良性软组织肿瘤在体内。虽然它们常见于上肢,但在手部却很少见。手的巨大脂肪瘤,定义为直径大于5厘米,是极其罕见的。本文报告一例罕见的手掌侧巨大脂肪瘤,以探讨其诊断、治疗及预后。61岁女性,10年来无症状大鱼际肿胀。临床检查显示皮下肿瘤扩散到第一连合,使拇指对指非常有限。没有炎症症状,也没有疼痛。患者无感觉障碍,神经学检查正常。标准x光片显示无骨损伤的组织图像。MRI显示一个大的,受限的T1, T2高信号组织形成,在第一连接的皮下脂肪中发展,在最后三个掌骨前,包括深屈肌腱和浅屈肌腱。患者在局部麻醉下行下肢根部气动止血带手术。该入路可以很好地暴露整个手掌,发现一个脂肪瘤状肿块,被包裹,将长指的血管和神经蒂向后推,而不侵犯它们,并保留在屈肌腱的前面。肿瘤被仔细地切开,从而得以完全切除。病理证实为良性脂肪瘤。随访5年,患者完全恢复,无复发迹象。摘要手部脂肪瘤是一种罕见的良性肿瘤。巨大的脂肪瘤是一种极为罕见的疾病。靠近血管和神经结构的关系必须在手术解剖时非常小心。只有解剖病理检查证实病变的组织学性质。
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Giant Lipoma of the Hand: An Exceedingly Rare Condition!
Lipomas are the most common benign form of soft tissue tumor in the body. Although they are commonly found on the upper extremity, their occurrence in the hand is rare. Giant lipomas of the hand, defined as >5 cm in diameter, are extremely rare. This manuscript reports a very rare case of giant lipoma on the palmar side of the hand in order to study the diagnostic, theurapeutic and prognostic aspects. A 61 year-old female had a large asymptomatic thenar swelling since 10 years. The clinical examination showed a subcutaneous tumor spreading the 1st commissure and making opposition of the thumb very limited. There were no inflammatory signs and no pain. The patient didn’t report any sensory deficit and the neurological examination was normal. The standard X-ray showed a tissue image without bone lesions. MRI demonstrated a large, well-limited T1, T2 hypersignal tissue formation, which developed in the subcutaneous fat of the first commissure, insinuated itself in front of the last three metacarpals, and included the deep and superficial flexor tendons. The patient was operated on under local anesthesia and pneumatic tourniquet at the root of the limb. The approach allowed a satisfactory exposure of the entire palm of the hand and revealed a lipomatous mass, encapsulated, pushing back the vascular and neural pedicles of the long fingers without invading them and remaining in front of the flexor tendons. The tumor was carefully dissected, which allowed it to be removed totally. Histology confirmed the diagnosis of benign lipoma. Complete recovery was achieved without any sign of recurrence during a follow up period of 5 years. Lipomas of the hand represent a rare benign tumor pathology; giant lipomas represent an exceedingly rare condition. The proximity of the relationships with the vascular and neural structures must lead to the greatest caution during surgical dissection. Only anatomopathological examinations confirm the histological nature of the lesion.
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