东爪哇省不同产地山茱萸提取物的抗癌活性研究

R. Mutiah, Fina Luthfiana, Arief Suryadinata, Wirda Anggraini, Anik Listiyana
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引用次数: 0

摘要

山茱萸(穿心莲)含有穿心莲内酯化合物,具有潜在的抗癌作用。生长位置的不同影响了代谢物含量的差异。本研究旨在确定爪哇东部不同产地的金针叶提取物的抗癌活性。采用MTT法检测不同部位提取物对T47D癌细胞的活性。因此,本研究结果说明,不同产地的金针叶提取物的抗癌活性随其含量的变化无显著差异(p>0.05)。具有中等抗癌活性的提取物分别为:Selopuro街道Blitar Regency、singosari街道Malang Regency、Lowokwaru街道Malang City、Klojen街道Malang City、Purwodadi街道Pasuruan Regency、Purwosari街道Pasuruan Regency和pandaan街道Pasuruan Regency
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The Profile of Anticancer Activities of Sambiloto Extract (Andrographis paniculata Nees) from Several Locations in East Java
Sambiloto (Andrographis paniculata Nees) contains andrographolid compound which has potentialas an anticancer. The difference of growth location has affected the distinction of metabolite content. Thisstudy aims to determine the profile of anticancer activities of A. paniculata extract from several locations inEast Java. The extracts from several locations were tested for activity on T47D cancer cell using MTT assaymethod. Thus, the result of this study describes that A. paniculata extract from several different locations doesnot provide significantly different anticancer activities with the amount of (p>0.05). The extracts which havemoderate anticancer activity were A. paniculata extracts from Selopuro Subdistrict Blitar Regency, SingosariSubdistrict Malang Regency, Lowokwaru Subdistrict Malang City, Klojen Subdistrict Malang City,Purwodadi Subdistrict Pasuruan Regency, Purwosari Subdistrict Pasuruan Regency, and PandaanSubdistrict Pasuruan Regency
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