基于超参数调谐网格搜索的支持向量机DNA序列分类分析

Iis Setiawan Mangkunegara, P. Purwono
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引用次数: 3

摘要

病毒和细菌在世界上不断进化。早期识别病原体是一种可以用来将疾病传播到药物设计的方法。DNA序列分类是计算生物学的一个重要方面。将测序基因组与NCBI数据进行比对,鉴定病原菌。机器学习技术可以对性质不明确的DNA进行分类,而且序列被认为很长,很难找到。本文提出了支持向量机分类模型。结果精度仍然被认为不是最优的,因此需要进行优化。与以往的研究相比,我们在SVM分类模型上使用了网格搜索cv优化技术。2度核多项式是网格搜索cv技术推荐的最佳参数。优化前的准确率为77%,优化后的准确率为90%。这表明,将网格搜索cv方法应用于使用SVM模型的DNA序列分类后,准确率提高了14%。
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Analysis of DNA Sequence Classification Using SVM Model with Hyperparameter Tuning Grid Search CV
Viruses and bacteria are constantly evolving in the world. Early identification of pathogens is one way that can be used to spread the spread of disease to drug design. DNA sequence classification is an essential aspect of computational biology. Pathogen identification was carried out by comparing data between sequenced genomes with NCBI data. Machine learning technology can classify DNA whose nature is unclear, and the sequence is considered long and challenging to find. The SVM classification model is proposed in this study. The resulting accuracy is still considered not optimal, so optimization is needed. In contrast to previous studies, we used the grid search cv optimization technique on the SVM classification model. Kernel polynomial with 2 degrees is the best parameter recommendation from the grid search cv technique. The accuracy before the optimization is 77%, while it is 90% after optimization. This shows an increase in accuracy of 14% after applying the grid search cv method to DNA sequence classification using the SVM model.
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