甲状腺激素对离体大鼠脂肪细胞5′-核苷酸酶的影响。

Enzyme Pub Date : 1992-01-01 DOI:10.1159/000468792

J M Gandarias, J J Goiriena, E Rueda, B M Fernandez

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引用次数: 0

摘要

测定正常、甲状腺功能减退和甲状腺功能亢进大鼠离体脂肪细胞中的5′-核苷酸酶。这样做是为了找出甲状腺激素是否对脂肪细胞产生腺苷有影响。结果表明，大鼠注射3,3'，5-三碘- l -甲状腺原氨酸(T3)后，5 '-核苷酸酶发生了修饰。在甲状腺功能减退或在细胞孵育中加入T3时，酶没有变化。

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Effect of thyroid hormones on 5'-nucleotidase of isolated rat fat cells.

5'-Nucleotidase was measured in isolated fat cells from normal, hypothyroid and hyperthyroid rats. This was done to find out whether thyroid hormones had an effect on the production of adenosine by the fat cell. The results showed that 5'-nucleotidase is modified when the rats received injections of 3,3',5-triiodo-L-thyronine (T3). There was no change in the enzyme in hypothyroidism or when T3 was added to incubation of cells.

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