抗病毒药物在抗击SARS-CoV-2中的作用

Sweta Kamboj, R. Kamboj, Shikha Kamboj, R. Dutt, Reeva Chabbra, P. Kriplani
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引用次数: 0

摘要

病毒是寄生的最终证明,它们不仅从宿主细胞中获取营养,而且还指导宿主细胞的代谢机制来合并新的病毒颗粒,并在个体中使用抗病毒药物来减少流感病毒的繁殖能力。如果按照指示使用,抗病毒药物可能有助于缩短流感症状的持续时间,并可能减轻普通流感症状的严重程度。抗病毒药物是在抗菌剂之下的一类药物,它也包括更大的一类药物,即抗生素。它们本质上是广谱的,可以有效对抗多种病毒。它们既可以作为单一药物使用,也可以作为药物组合使用。抗病毒药物不同于抗生素,它们不能理想地摧毁目标病原体,而是阻碍病原体的发展。目前可获得的抗病毒药物在最大程度上用于治疗疱疹病毒、covid-19、艾滋病毒、乙型肝炎和丙型肝炎病毒、单纯疱疹病毒、天花、小核糖核酸病毒以及甲型和乙型流感病毒等。科学家们正在努力将抗病毒药物的范围扩大到其他病原体家族。它们的作用主要是抑制病毒附着在细胞上,阻止病毒的遗传繁殖,阻止病毒蛋白的产生,对病毒的产生至关重要。抗病毒药物的出现通常是对生物体的生殖、微观和原子活动的技能或熟练程度的显著扩展的结果,使生物医学分析人员能够认识到病毒的结构、作用机制和活性,在遇到当前药物的过程中取得了重大进展。冠状病毒2019 (COVID - 19)是由SARS-CoV-2(严重急性呼吸综合征)冠状病毒2引发的高度传染性疾病,在全球造成近290万人死亡。随着SARS-CoV-2的出现,抗病毒药物的重新用途已经进入人们的视野。
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Role of Anti-Viral Drugs in Combating SARS-CoV-2
Viruses are the eventual assertion of parasitism, they not only take nutriments from the host cell, apart from that they direct its metabolic machinery to amalgamate novel virus particle and to diminish the ability of flu viruses to reproduce in an individual antiviral drugs are used. When used as directed, antiviral drugs may help to lessen the duration of flu symptoms and may reduce the severity of common flu symptoms. Antiviral drugs are the class of drugs which comes under the antimicrobials, and that also accommodates the larger group i.e. of antibiotics. They are broad-spectrum in nature and can be effective against a wide range of viruses. They can be used as a single drug as well as in combination of drugs. Antiviral drugs are dissimilar from the antibiotics, they do not demolish their target pathogen ideally they obstruct development of pathogen. To the greatest extent antiviral drugs currently accessible are delineate to deal with herpes viruses, covid-19, HIV, the hepatitis b and c viruses herpes simplex, small pox, picornavirus and influenza a and b viruses etc. Scientists are searching to drag out the range of antiviral to the other families of pathogens. They mainly act by inhibiting the attachment of viruses on cells, prevent genetic reproduction of virus, prevent viral protein production and vital for production of virus. The emanation of antiviral is generally the outcome about an appreciably expanded skills or proficiency of the generative, microscopic and atomic activity of organisms, allowing biomedical analyst to acknowledge the structure, mechanism of action and activity of viruses, significant progress within the procedure for come across the current drugs. Coronavirus 2019 (COVID 19) is highly infectious disease triggered by SARS-CoV-2 (severe acute respiratory syndrome) coronavirus 2 causing nearly 2.9 million deaths worldwide. With the emergence of SARS-CoV-2, the repurposing of antiviral drugs has come into picture.
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Current Status of COVID-19 Diagnostics Role of Anti-Viral Drugs in Combating SARS-CoV-2 Epigenetic Regulation Mechanisms in Viral Infections: A Special Focus on COVID-19 Consequence of Meteorological Parameters on the Transmission of Covid-19 Application of Ex-Vivo/3D Organoid Models in COVID-19 Research
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