S Suski, T Zawadowski, M Bogdal, B Przemyk, B Szafrański
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Synthesis and central pharmacological screening of new aminoalkoxy derivatives of coumarin and chromene.
Several 8-(2- and 3-aminoalkoxy) derivatives of coumarin and 5-(2- and 3-aminoalkoxy) derivatives of chromene have been synthesized. The strongest, although short-time neurodepressive activity was exhibited by 8-[3-(4-phenyl-1-piperazinyl)propoxy]-7-methoxycoumarin hydrochloride 15.
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