1420在黑色素瘤中，靶向内质网应激反应性PERK可诱导旁噬介导的免疫原性细胞死亡和I型干扰素依赖性适应性抗肿瘤免疫

{"title":"1420在黑色素瘤中，靶向内质网应激反应性PERK可诱导旁噬介导的免疫原性细胞死亡和I型干扰素依赖性适应性抗肿瘤免疫","authors":"J. Mandula, Shiun Chang, Eslam Mohamed, Rachel Jiminez, Rosa Sierra-Mondragon, Darwin Chang, Alyssa N. Obermayer, Carlos Moran-Segura, Das Satyajit, J. Vázquez-Martínez, Karol Pierto, Ann J Chen, K. Smalley, B. Czerniecki, P. Forsyth, R. Koya, B. Ruffell, J. Cubillos-Ruiz, D. Munn, Timothy I. Shaw, J. Conejo-Garcia, P. Rodriguez","doi":"10.1136/jitc-2022-sitc2022.1420","DOIUrl":null,"url":null,"abstract":"","PeriodicalId":398566,"journal":{"name":"Regular and Young Investigator Award Abstracts","volume":"83 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"1420 Targeting endoplasmic reticulum stress-responsive PERK in melanoma elicits paraptosis-mediated immunogenic cell death and induction of type I interferon-dependent adaptive antitumor immunity\",\"authors\":\"J. Mandula, Shiun Chang, Eslam Mohamed, Rachel Jiminez, Rosa Sierra-Mondragon, Darwin Chang, Alyssa N. Obermayer, Carlos Moran-Segura, Das Satyajit, J. Vázquez-Martínez, Karol Pierto, Ann J Chen, K. Smalley, B. Czerniecki, P. Forsyth, R. Koya, B. Ruffell, J. Cubillos-Ruiz, D. Munn, Timothy I. Shaw, J. Conejo-Garcia, P. Rodriguez\",\"doi\":\"10.1136/jitc-2022-sitc2022.1420\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"\",\"PeriodicalId\":398566,\"journal\":{\"name\":\"Regular and Young Investigator Award Abstracts\",\"volume\":\"83 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-11-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Regular and Young Investigator Award Abstracts\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1136/jitc-2022-sitc2022.1420\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Regular and Young Investigator Award Abstracts","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1136/jitc-2022-sitc2022.1420","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}