人工神经网络在丙型肝炎诊断中的应用

Amela Drobo, L. S. Becirovic, L. G. Pokvic, Lucija Dzambo, E. Becic, A. Badnjević, Majda Dogic, Alisa Smajovic
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引用次数: 0

摘要

丙型肝炎是一种由丙型肝炎病毒引起的肝脏炎症。该病本身诊断困难,因为潜伏期长,往往该病最初没有一些特征性症状,而且还由于缺乏实验室方法。如今,越来越多的人使用人工智能来更容易、更快地评估疾病。由于丙型肝炎是一个日益增加的医疗负担,因此建立有效可靠的筛查方法至关重要。由于人工智能已被证明可用于基于临床参数的多种疾病诊断,因此本研究侧重于人工神经网络(ANN)在丙型肝炎诊断中的应用。在这项研究中,1000名受访者的数据库被分为两组:健康(n = 200)和疾病(n = 800)来开发人工神经网络。监测参数为:白蛋白、碱性磷酸酶、丙氨酸转氨酶、天冬氨酸转氨酶、胆红素、乙酰胆碱酯酶、抗hcv抗体。所开发的人工神经网络的总体准确率为97,78%,这表明人工智能在丙型肝炎诊断中的潜力巨大,未来应重视开发具有尽可能多数据的新系统。
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Application of artificial neural networks in diagnosis of Hepatitis C
Hepatitis C is an inflammatory condition of the liver caused by the hepatitis C virus. Diagnosis of the disease itself is difficult because the incubation period is long, often the disease is initially without some characteristic symptoms, but also due to a lack of laboratory methods. Artificial intelligence is increasingly being used nowadays to make it easier and faster to assess the illness. As hepatitis C is a rising healthcare burden it is of utmost importance to construct effective and reliable screening methods. As AI has already proven useful for diagnosis of a variety of conditions based on clinical parameters, this study focuses on the application of artificial neural network (ANN) for hepatitis C diagnosis. In this study, a database of 1000 respondents divided into two groups was used to develop the ANN: healthy (n = 200) and sick (n = 800). Monitoring parameters were: albumin, alkaline phosphatase, alanine aminotransferase, aspartate aminotransferase, bilirubin, acetylcholinesterase and anti-HCV antibodies. The overall accuracy of the developed ANN was 97,78%, which indicates that the potential of artificial intelligence in diagnosing hepatitis C is enormous, and in the future, attention should be paid to the development of new systems with as much data as possible.
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