基于嵌入式钝化电极绝缘体的电介质电泳(epπ dep)对乳腺癌细胞的处理

2013 IEEE SENSORS Pub Date : 2013-12-19 DOI:10.1109/ICSENS.2013.6688314

Tyler Shake, V. Srinivasaraghavan, P. Zellner, M. Agah

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引用次数: 1

摘要

本文介绍了一种新型的嵌入式钝化电极绝缘介质电泳(epπ dep)装置，用于细胞操作。该器件通过将钝化层厚度减小到5μm，使微流控通道内的电场强度最大化。这些装置是通过聚合物模塑制成的，使用3D玻璃模具，通过将玻璃熔化成硅上的RIE-lag技术产生的特征而制成。本文演示了利用π - dep技术捕获MDA-MB-468乳腺癌细胞，其捕获效率高达97%。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Mammary cancer cell manipulation with embedded passivated-electrode insulator-based dielctrophoresis (EπDEP)

In this paper, we introduce a new embedded passivated-electrode insulator-based dielectrophoresis (EπDEP) device for cell manipulation. This device maximizes the electric field strength in the microfluidic channel by reducing the thickness of the passivation layer to 5μm. The devices are made by polymer molding using 3D glass molds fabricated by melting glass into features created by the RIE-lag technique on silicon. This paper demonstrates the trapping of MDA-MB-468 mammary cancer cells using EπDEP technology with very high efficiency (97%).

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2013 IEEE SENSORS

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