标准化,患者特异性,住院骨科手术后阿片类药物处方。

E. Y. Chen, L. Betancourt, Lulu Li, Emma Trucks, Andrew J. Marcantonio, P. Tornetta
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引用次数: 22

摘要

在过去的20年里,阿片类药物相关的死亡率有所增加,导致人们认识到全国性的阿片类药物流行,并促使医生重新审视他们的阿片类药物处方做法。在我们的机构,我们没有关于住院骨科手术后出院时开具阿片类药物处方的协议,导致处方不一致和潜在的过量。在这里,我们报告了使用阿片类药物锥形计算器来标准化住院骨科手术后出院时阿片类药物处方的患者特定方案的实施结果。方法阿片类药物用量计算器是一种基于每个患者24小时出院前阿片类药物使用情况创建患者特异性阿片类药物用量的工具。我们在我们的两个机构(波士顿医疗中心、勒希医院和伯灵顿校区医疗中心)对住院骨科手术后出院的患者实施了这种减少。我们比较了骨科患者在实施后和实施前的阿片类药物数量。我们还比较了同一时期骨科和非骨科手术服务的出院阿片类药物数量。结果实施9个月后,74%的符合条件的出院患者使用了患者特异性减量,导致出院时阿片类药物处方减少24%,方差减少35%。在同一时间段内,非骨科服务出院时开具的阿片类药物减少幅度较小(9%)。在全关节置换术和脊柱融合术后观察到最显著的下降。尽管减少了,但大多数患者(65%)报告获得了足够的阿片类药物,出院后30天阿片类药物处方再填充在方案实施后与实施前没有实质性变化(每次出院1.58次对1.71次)。使用阿片类药物用量计算器,患者特异性用量可以成功地用于标准化住院骨科手术后出院时的阿片类药物处方,而不会出现处方不足的重大风险。证据等级:II级。
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Standardized, Patient-specific, Postoperative Opioid Prescribing After Inpatient Orthopaedic Surgery.
BACKGROUND Opioid-related mortality has increased over the past 2 decades, leading to the recognition of a nationwide opioid epidemic and prompting physicians to reexamine their opioid prescribing practices. At our institutions, we had no protocol for prescribing opioids upon discharge after inpatient orthopaedic surgery, resulting in inconsistent and potentially excessive prescribing. Here, we report the results of the implementation of a patient-specific protocol using an opioid taper calculator to standardize opioid prescribing at discharge after inpatient orthopaedic surgery. METHODS The opioid taper calculator is a tool that creates a patient-specific opioid taper based on each patient's 24-hour predischarge opioid utilization. We implemented this taper for patients discharged after inpatient orthopaedic surgery at our two institutions (Boston Medical Center and Lahey Hospital and Medical Center-Burlington Campus). We compared discharge opioid quantities between orthopaedic patients postimplementation and quantities prescribed preimplementation. We also compared discharge opioid quantities between orthopaedic and nonorthopaedic surgical services over the same time period. RESULTS Nine-months postimplementation, a patient-specific taper was used in 74% of eligible discharges, resulting in a 24% reduction in opioids prescribed at discharge, along with a 35% reduction in variance. Over the same time frame, a smaller reduction (9%) was seen in the opioids prescribed at discharge by nonorthopaedic services. The most notable reductions were seen after total joint arthroplasty and spinal fusions. Despite this reduction, most patients (65%) reported receiving sufficient opioids, and no substantial change was observed in 30-day postdischarge opioid prescription refills after versus before protocol implementation (1.58 versus 1.71 fills per discharge). DISCUSSION Using the opioid taper calculator, a patient-specific taper can be successfully used to standardize opioid prescribing at discharge after inpatient orthopaedic surgery without a substantial risk of underprescription. LEVEL OF EVIDENCE Level II.
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