大戟注射液对小鼠创伤血瘀模型的影响

M. Miao, Bolin Cheng, M. Bai
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摘要

目的:研究大戟对创伤性血瘀模型的影响。方法:造模后,测量各组大鼠右后腿周长并记录。同时,我们处理症状积分。每组大鼠每天给药1次,连续给药5天,2小时内保持药贴皮肤。成型后,在饲养和治疗期间,观察肿胀、瘀斑等症状,每两天记录一次周长和症状积分。敷药第6天,取眼球血,做血液流变学检查,组织病理观察。结果:不同剂量大戟精对各组大鼠右后腿损伤症状积分及premier均有明显降低。血液流变学指标能减轻血瘀,使皮肤及角质层鳞状上皮保持正常,皮下组织水肿恢复。结论:大麻子对创伤性血瘀模型有较好的治疗作用。
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The effect of Semen Euphorbiae cataplasm on mice model of trauma blood stasis
Objective: to research the effect of Semen Euphorbiae on model of traumatic blood stasis. Method: After moulding, we measure the perimeters of the right rear leg of every group rats and record them. Meanwhile, we process the Symptom Integral. We give suitable medicine to every group rats once a day in five days, and keep the medicine adhere to skin in two hours. After moulding, in the period of feed and cure, observe the swelling, ecchymosis and such symptoms, and record the perimeters and symptom integral every two days. In the sixth day of applying medicine, extract blood in the eyeball and examine it by hemorheology, and Pathological observation of the tissue. Result :The injure symptom integral and premier of right rear legs of every group rats with different dose of Semen Euphorbiae are decreased obviously. The indicators of hemorheology can reduce the blood stasis, and make the squamous epithelium in skin and cuticular layer to keep normal, and the subcutaneous tissue edema recovers. Conclusion: Semen Euphorbiae is very effective for traumatic blood stasis model.
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