感染相关性和肾限制性肾小球肾炎

R. Glassock, L. Hebert, G. Moroni, C. Ponticelli
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引用次数: 1

摘要

本章涵盖与感染有关的肾小球肾炎,其中包括广泛的流行病和地方病。细菌、真菌、原生动物、线虫、蠕虫和病毒都是造成肾小球疾病负担的原因。这些疾病大多有多种多样的肾外表现,通常被归类为继发性肾小球疾病。然而,少数主要或完全累及肾脏,可归为原发性肾小球疾病。这组肾小球疾病的特点是由多种生物体引发的免疫事件引起的肾小球内炎症和细胞增殖。本章讨论感染相关性肾小球肾炎的典型肾限制形式。
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Infection-related and renal-limited glomerulonephritis
This chapter covers the infection-related glomerulonephritides, which encompass a wide swath of epidemic and endemic diseases. Bacteria, fungi, protozoa, nematodes, helminths and viruses all contribute to the glomerular disease burden. Most of these have numerous and varied extra-renal manifestations and are commonly classified as secondary glomerular diseases. However, a few have mainly or exclusively renal involvement and can be classified within the rubric of primary glomerular disease. This group of glomerular diseases is characterized by intraglomerular inflammation and cellular proliferation resulting from immunological events triggered by a variety of organisms. This chapter discusses the prototypical renal-limited forms of infection-related glomerulonephritis.
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The pharmacology of old and new agents for specific therapy of primary glomerular diseases A definition, modern classification, and global epidemiology of primary glomerulonephritis Infection-related and renal-limited glomerulonephritis C3 glomerulopathies and ‘idiopathic’ immune complex membranoproliferative glomerulonephritis (MPGN) Renal-limited vasculitis (RLV)
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