硫代硫酸钠对口蹄疫病毒斑块增强作用的机制。

Microbiologica Pub Date : 1992-10-01
K Kadoi
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引用次数: 0

摘要

研究了先前报道的在琼脂覆盖培养基(AOM)中添加硫代硫酸钠(Hypo)增强口蹄疫病毒(FMDV)菌斑的机制。实验证明,当加入该盐时,病毒颗粒在琼脂覆盖介质中的扩散增强。因此,斑块形成的扩大被认为是由在斑块检测期间在感染中心产生的病毒子代扩散增强引起的。
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A mechanism involved in the plaque enhancement effect of sodium thiosulfate for foot-and-mouth disease viruses.

A mechanism involved in the plaque enhancement effect of foot-and-mouth disease viruses (FMDV) by the addition of sodium thiosulfate (Hypo) in the agar overlay medium (AOM) previously reported was studied. It was experimentally proved that the diffusion of virus particles through agar overlay medium was enhanced when this salt was incorporated. Accordingly, the enlarged plaque formation was assumed to be caused by the enhanced diffusion of viral progenies produced in infectious centers during plaque assays.

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