溴隐亭治疗前后纤维囊性乳腺病变的组织学改变。

Revista paulista de medicina Pub Date : 1992-11-01
E F Murta, M M de Freitas, M A Velludo
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引用次数: 0

摘要

在一项双盲研究中,25名患有纤维囊性乳腺疾病的妇女使用溴隐亭(5 - 7.5 mg/天,持续3个月)或安慰剂治疗。雌二醇和黄体酮的测量在治疗前、治疗期间和治疗后没有任何变化。在使用溴隐亭期间血清催乳素水平降低。组织学评估显示上皮增生减少,经溴隐亭治疗后囊性扩张图像停止。
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Histologic changes in fibrocystic breast disease before and after treatment with bromocriptine.

Twenty-five women with fibrocystic breast disease were investigated in a double-blind study using treatment with bromocriptine (5 to 7.5 mg/day for 3 months) or placebo. Estradiol and progesterone measurements did not show any changes before, during or after treatment. Serum prolactin levels were reduced during the use of bromocriptine. Histologic evaluation demonstrated a decrease of epithelial hyperplasia and arrest of the cystic dilation picture after treatment with bromocriptine.

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