Pathogenesis and Nutritional Intervention of Chronic Obstructive Pulmonary Disease-Associated Frailty

Frailty, as a type of geriatric condition, has been a major focus of geriatrics researchers in recent years. COPD is one of the major risk factors associated with frailty. Consequently, chronic obstructive pulmonary disease-related frailty has become the focal point of numerous investigations. However, the majority of studies focus on cross-sectional investigations of the incidence of frailty in COPD and their associations. The study of its pathophysiology and intervention methods is dispersed, and there is a paucity of literature reviews. Moreover, in-depth research into the pathophysiology of such patients and the implementation of efficient therapeutic strategies are crucial for enhancing the long-term quality of life of patients. The purpose of this article is to provide a reference for creating nutritional intervention programs for chronic obstructive pulmonary disease and a debilitated population by describing the etiology of these patients and summarizing potential nutritional therapies based on recent research.