全髋关节置换术中多孔钽与多孔钛髋臼植入材料的力学与骨整合性能比较:文献综述

Margaret S. Juryn
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摘要

前言:髋臼假体的稳定性是初次和翻修全髋关节置换术成功的关键因素。因此,确定种植体表面特征,最大限度地提高髋臼杯的稳定性是一个重要的研究目标。虽然钛历来是最常用的植入材料,但近年来使用多孔钽(PTa)植入物的THA手术比例有所增加。本综述的目的是比较PTa和多孔钛(PTi)的力学和骨整合性能,并在髋关节置换术中髋臼植入物的初级和次级稳定性的背景下解释这些结果,其特征分别是初始机械附着强度和骨-植入物界面的成功联锁。方法:使用预先确定的方案和纳入标准进行文献检索,获得7篇文章,介绍了THA背景下PTa和PTi的机械性能或骨整合的比较测试结果。结果:无论是PTa还是PTi,在与金属生物表面的初级稳定性相关的机械测试中,还是在旨在代表THA的二级稳定性的骨整合测量中,都没有表现出一贯的优越结果。讨论:在PTa和PTi的比较中,我们发现与所选择的金属相比,植入物涂层孔隙的特性可能对髋臼杯植入物稳定性的影响因素更为显著。然而,确定这种应用的理想孔隙形态是复杂的;表明机械相容性的孔隙特征可能与那些促进更有效骨整合的孔隙特征相冲突。结论:当外推作为假设临床成功的指标时,本综述的结果与最近发布的临床结果的宏观分析结果一致:PTa和PTi髋臼杯,就其目前的生产而言,产生了临床等效的结果。在开发和比较涂层选择时,必须充分考虑孔隙形态及其对稳定性的复杂影响;只有这样,我们才能得出髋关节置换术中理想的多孔附着面。
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Comparison of the Mechanical and Osseointegrative Performance of Porous Tantalum and Titanium for Acetabular Implantation in Total Hip Arthroplasty: A Literature Review
Introduction: Stability of the acetabular component is a critical factor in the success of primary and revision total hip arthroplasty (THA) procedures. As such, the identification of implant surface characteristics that maximize stability of the acetabular cup is an important research objective. While titanium has historically been the most commonly used implant material, the proportion of THA procedures utilizing porous tantalum (PTa) implants has increased in recent years. The objective of this review is to examine the comparative mechanical and osseointegrative performance of PTa and porous titanium (PTi) and interpret these results in the context of primary and secondary stability of acetabular implants in THA, as characterized by strength of initial mechanical attachment and successful interlocking at the bone-implant interface, respectively. Methods: A literature search using a predetermined protocol and inclusion criteria yielded 7 articles presenting results of comparative testing of mechanical performance or osseointegration of PTa and PTi in the context of THA. Results: Neither PTa nor PTi presented consistently superior results in mechanical tests designed to correlate to primary stability at the metallo-biological surface nor in measures of osseointegration intended to represent secondary stability in THA. Discussion: In comparing PTa and PTi, it appears that the characteristics of the implant coating's pores may have a more significant impact on factors affecting the stability of an acetabular cup implant than the metal selected. However, determining the ideal pore morphology for this application is complex; pore characteristics that would suggest mechanical compatibility may conflict with those that would encourage more effective osseointegration. Conclusion: When extrapolated to be indicators of hypothetical clinical success, the results of this review are consistent with those of recently released macro-analyses of clinical outcomes: PTa and PTi acetabular cups, as they are currently manufactured, produce clinically equivalent outcomes. In the development and comparison of coating options, pore morphology and its complex effects on stability must be adequately accounted for; only then can we reach a faithful conclusion regarding the ideal porous adhesion surface for acetabular implant in THA.
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