产16S rRNA甲基化酶革兰氏阴性杆菌的分子和表型特征

Hyukmin Lee, E. Koh, Chang Ki Kim, J. Yum, Kyungwon Lee, Y. Chong
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引用次数: 2

摘要

最近报道了一种新的质粒介导的耐药机制,该机制通过16S rRNA的甲基化赋予了对氨基糖苷的高水平抗性。本研究的目的是确定革兰氏阴性杆菌中16S rRNA甲基化酶基因的流行率,并表征对其他抗生素的共耐药。
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Molecular and Phenotypic Characteristics of 16S rRNA Methylase-producing Gram-negative Bacilli
Recently a novel plasmid-mediated re-sistant mechanism that conferred high-level resist-ance to aminoglycoside via methylation of 16S rRNA was reported. The aims of this study were to de-termine the prevalence of the 16S rRNA methylase genes and to characterize the coresistance to other antibiotics in Gram-negative bacilli.
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