老年性核性白内障晶状体蛋白中不寻常的有色化合物。

Lens and eye toxicity research Pub Date : 1992-01-01
R J Truscott, E Langenberg
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引用次数: 0

摘要

通过吸附到Sephadex G-10上,从老年性白内障核蛋白的蛋白水解消化物中分离出一种不寻常的粉红色化合物。所获得的微量物质妨碍了明确的结构解析,然而薄层色谱比较表明它类似于三吩二恶嗪-1,8-二羧酸,一种由3-羟基苯甲酸氧化缩合形成的粉红色杂环化学物质。
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An unusual coloured compound in digests of senile nuclear cataract lens proteins.

An unusual pink compound has been isolated from the proteolytic digests of senile nuclear cataract proteins by adsorption onto Sephadex G-10. The tiny amounts obtained precluded definitive structural elucidation, however TLC comparisons show that it resembles triphenodioxazine-1,8-dicarboxylic acid, a pink heterocyclic chemical formed by oxidative condensation of 3-hydroxyanthranilic acid.

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