The Role of Radiation Therapy and Stereotactic Radiosurgery in the Treatment of Pituitary Adenomas

Pituitary tumors can be managed with medication, surgical resection, radiation therapy (XRT), and stereotactic radiosurgery. Radiation approaches are best suited for patients with residual tumors after prior resection, particularly when the tumor involves the cavernous sinus. Irradiation can also be useful for patients with persistent hormone-secreting tumors despite resection or in those for whom resection would be associated with excessive risk. In this report, we review the rationale behind the various radiation approaches and discuss the risks and benefits of radiosurgery and XRT.