{"title":"人类基因组计划的颠覆性反思","authors":"Alexander B. Rosenberg","doi":"10.1086/PSAPROCBIENMEETP.1994.2.192943","DOIUrl":null,"url":null,"abstract":"By developing an elaborate allegory, this paper attempts to show that the advertised aim of the Human Genome project, to sequence the entire 3 billion base pair primary sequence of the nucleic acid molecules that constitute the human genome, does not make scientific sense. This raises the questions of what the real aim of the project could be, and why the molecular biological community has chosen to offer the primary sequence as the objective to be funded, when identifying functionally important sub-regions of the genetic material is both far more useful and independently attainable an aim.","PeriodicalId":288090,"journal":{"name":"PSA: Proceedings of the Biennial Meeting of the Philosophy of Science Association","volume":"2 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":"{\"title\":\"Subversive Reflections on the Human Genome Project\",\"authors\":\"Alexander B. Rosenberg\",\"doi\":\"10.1086/PSAPROCBIENMEETP.1994.2.192943\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"By developing an elaborate allegory, this paper attempts to show that the advertised aim of the Human Genome project, to sequence the entire 3 billion base pair primary sequence of the nucleic acid molecules that constitute the human genome, does not make scientific sense. This raises the questions of what the real aim of the project could be, and why the molecular biological community has chosen to offer the primary sequence as the objective to be funded, when identifying functionally important sub-regions of the genetic material is both far more useful and independently attainable an aim.\",\"PeriodicalId\":288090,\"journal\":{\"name\":\"PSA: Proceedings of the Biennial Meeting of the Philosophy of Science Association\",\"volume\":\"2 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1994-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"PSA: Proceedings of the Biennial Meeting of the Philosophy of Science Association\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1086/PSAPROCBIENMEETP.1994.2.192943\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"PSA: Proceedings of the Biennial Meeting of the Philosophy of Science Association","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1086/PSAPROCBIENMEETP.1994.2.192943","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Subversive Reflections on the Human Genome Project
By developing an elaborate allegory, this paper attempts to show that the advertised aim of the Human Genome project, to sequence the entire 3 billion base pair primary sequence of the nucleic acid molecules that constitute the human genome, does not make scientific sense. This raises the questions of what the real aim of the project could be, and why the molecular biological community has chosen to offer the primary sequence as the objective to be funded, when identifying functionally important sub-regions of the genetic material is both far more useful and independently attainable an aim.