一种用于芯片实验室的新型小型化行波介质电泳微分离器

E. Poorreza, R. H. Vafaie, M. Mehdipoor, A. Pourmand, H. B. Ghavifekr
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引用次数: 8

摘要

颗粒分离是高度小型化的通道系统所面临的挑战。由于缓冲流体的雷诺数很低,基于行波介质电泳效应的微分离器在此类应用中具有很好的充分性。本文将基于表面微加工的微通道技术改进为微分离器。由于制造工艺的原因,由高掺杂多晶硅制成的电极被薄的氮化硅层覆盖。研究了薄隔离层对微分离器功能的影响。仿真结果表明,当缓冲液的电导率低于1μs/m时,在1MHz频率范围内可以实现较好的分离。介绍了隔膜的制作工艺,并讨论了流体介电常数和偏置电压等参数对隔膜运行的影响。
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A novel miniaturized travelling wave dielectrophoresis microseparator for lab-on-a-chip applications
Particle separation is a challenge by highly miniaturized channel systems. Due to very low Reynolds number of buffer fluid, microseparators based on travelling wave dielectrophoresis effect have a good sufficiency in such applications. In this paper a microchannel technique based on surface micromachining is modified to a microseparator. Due to fabrication process the electrodes made of highly doped polysilicon are covered by a thin silicon-nitride layer. The influence of this thin isolating layer on functionality of the microseparator is investigated. The simulation results indicate that a satisfied separation occurs in the frequency range of 1MHz, when electrical conductivity of buffer fluid is lower than 1μs/m. The fabrication process is presented and influences of other parameters such as permittivity of fluid and bias voltage on the operation of separator are discussed.
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