Pybertygenesis progress' peculiarities of adolescent girls with gynecological pathology, born low or high to gestational weight

The perinatal background plays one of the most important roles in the development of future mothers. The study of factors influencing the formation of puberty is an urgent issue for improving the demographic situation in the country. Purpose — to analyze the nature of the pubertogenesis's progress of adolescent girls depending on body weight at birth. Materials and methods. A retrospective analysis was made of the course of pregnancy and childbirth of mothers of girls born with low or overweight. Menstrual function and somatic status among the study groups were prospectively assessed to identify markers of start and puberty disorders. Results. The data obtained showed the reliability of the influence of body weight at birth on the development of menstrual function. Hypomenstrual syndrome was formed under the influence of fetal growth retardation syndrome, and vice versa, hypermenstrual syndrome was based on macrosomia in the antenatal period. Conclusions. The identified features provide an opportunity for further research for the timely optimization of the formation of risk groups in the fertile age. Step-by-step monitoring and predictive models for the formation and maintenance of the ovarian reserve of this cohort implement differentiated pregravid preparation at an early reproductive age. The research was carried out in accordance with the principles of the Helsinki declaration. The study protocol was approved by the Local ethics committee of the participating institution. The informed consent of the patient was obtained for conducting the studies. No conflict of interest was declared by the author. Key words: puberty, reproductive potential, low birth weight, macrosomia, menarche.