巴基斯坦伊斯兰堡哮喘控制对健康相关生活质量的影响:一项相关研究

A. Razzaq, Suman Sheraz, Mohsana Tariq
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摘要

背景:哮喘是一种以慢性炎症和哮喘反复发作为特征的支气管气道疾病。生活质量也受哮喘控制的影响。目的:探讨哮喘患者哮喘控制与健康相关生活质量的关系。方法:本描述性横断面研究在伊斯兰堡国立卫生研究院和伊斯兰堡联邦总医院进行。哮喘患者的年龄在15-40岁之间,患有哮喘至少6个月,服用过抗哮喘药物,并应在伊斯兰堡/拉瓦尔品第居住。患有心源性、肺源性或外伤性呼吸短促、任何皮肤病问题以及接受手术的受试者被排除在研究之外。采用乌尔都语版哮喘生活质量问卷(AQLQ)计算哮喘患者的生活质量。研究时间为6个月,采用方便抽样的方式,通过G-Power计算出100例哮喘患者。采用SPSS统计软件Spearman相关统计分析健康相关生活质量与哮喘控制之间的关系。结果:哮喘患者中,31%的患者哮喘未控制,63%的患者哮喘症状部分控制,仅有6%的患者哮喘得到控制。相关值r = 0.886表明哮喘控制与生活质量之间存在较强的相关性。P<0.05,相关性强且显著。哮喘未控制时生活质量较差(2.12±0.36),哮喘控制时生活质量较好(5.46±0.30)。结论:与哮喘症状控制不佳的患者相比,控制哮喘患者的生活质量更好。这些哮喘患者在情绪、环境和活动限制的所有领域的生活质量都较差。
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Impact of asthma control on health related quality of life in Islamabad, Pakistan: A correlational study
Background: Asthma is a bronchial airways disease which is characterized by chronic inflammation and repetitive Asthma attacks. Quality of life is also affected by asthma control. Objective: The objective is to determine the correlation of the asthma control with the health-related quality of life in Asthma patients. Methods: This descriptive cross-sectional study was conducted at N.I.H Islamabad and Federal General Hospital Islamabad. The asthmatic patients who had suffered from asthma for at least 6 months and were aged between 15-40 years, had received anti-asthmatic drugs and should have had residence at Islamabad/Rawalpindi were included. The subjects having cardiac, pulmonary or traumatic shortness of breath, any dermatological issues and those undergoing surgery were excluded from the study. The quality of life of asthmatic people was calculated using Urdu version of Mini Asthma Quality of Life Questionnaire (AQLQ). The study was spread over 6 months and 100 asthmatic patients, calculated through G-Power, were selected in the survey through convenience sampling. Spearman's correlation statistics on SPSS was used to find relation between health related quality of life and control on asthma Results: Out of total patients, 31% asthma patients had uncontrolled asthma and 63% had partially control asthma symptoms and only 6% with controlled asthma. The correlational value of r = 0.886 shows a strong relationship between control on asthma and quality of life. P<0.05 so relationship is strong and significant. Quality of Life was poorer when the asthma was uncontrolled (2.12± 0.36) and it was better (5.46±0.30) when asthma was controlled. Conclusion: The study concluded that the patient's with controlled asthma had better quality of life as compared to the patients with poor control on asthma symptoms. These asthmatic patients had poor quality of life in all domains of emotional, environmental and activity limitation.
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