计算机断层扫描引导射频消融治疗骨样骨瘤:初步结果

A. El Naggar, M. Shaban
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摘要

骨样骨瘤(Osteoid osteoma, OO)是一种成骨性骨肿瘤。临床表现为夜间疼痛,经非甾体抗炎药治疗后疼痛改善。在x线摄影上表现为周围骨硬化的小透光病灶。手术切除是经典的治疗选择。然而,许多非侵入性手术已被用于避免与手术治疗相关的发病率。本研究的目的是评估改良射频消融技术(RFA)在治疗OO中的疗效。患者与方法采用经皮计算机断层扫描引导下的射频消融术治疗37例OO患者。总的来说,24例病灶位于股骨,10例位于胫骨,2例位于髋臼,1例位于肩胛骨。诊断依据临床症状、x线片、计算机断层扫描和骨显像。骨钻是用来做一个轨道,以达到病灶。平均随访37个月。结果36例患者术后3周12 h内疼痛消失。一名患者的疼痛程度较轻。一名患者有短暂性坐骨神经痛,使用皮质类固醇和非甾体抗炎药改善。2例患者使用抗生素治疗软组织感染。至少2.5年未见复发。结论射频消融是一种安全有效的治疗OO病变的方法,特别是对于手术治疗困难的病变。骨钻的使用简化了技术,减少了手术时间。
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Computerized tomography-guided radiofrequency ablation for osteoid osteoma: preliminary results
Background Osteoid osteoma (OO) is an osteogenic bone tumor. Clinically, it is characterized by night pain that improves with NSAID treatment. It appears in radiography as a small radiolucent nidus with sclerosis of the surrounding bone. Surgical excision is the classic treatment of choice. However, many noninvasive procedures have been used to avoid the morbidity associated with surgical treatment. The aim of this study was to evaluate the efficacy of modified technique of radiofrequency ablation (RFA) in the management of OO. Patients and methods A total of 37 patients with OO were treated with percutaneous computed tomography-guided RFA. Overall, 24 lesions were located in the femur, 10 in the tibia, two in the acetabulum, and one in scapula. The diagnosis was based on clinical symptoms, radiographs, computed tomography scan, and bone scintigraphy. Bone drilling was used to make a track to reach the nidus. The average follow-up period was 37 months. Results A total of 36 patients became pain free within a period of 12 h 3 weeks after the procedure. One patient experienced a milder form of pain. One patient had transient sciatica, which improved using corticosteroids and NSAIDs. Two patients had soft tissue infection treated using antibiotics. No recurrence was reported for at least 2.5 years. Conclusions RFA is a safe and effective treatment for OO lesions, especially for lesions, which is difficult to be managed surgically. The use of a bone drill facilitates the technique and decreases the operative time.
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