儿童脊椎关节炎

Walter Alberto Sifuentes Giraldo, María Luz Gámir Gámir
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引用次数: 0

摘要

青少年性脊柱炎是脊柱炎概念中包含的一个特殊群体,其特征主要是外周受累(关节炎和骨髓炎),并且更常以未分化形式出现。然而,与成人发病的同类疾病一样,它有可能发展为结构损伤并发展为青少年强直性脊柱炎,从而导致不可逆转的功能损害。许多重要的进展已经取得了对遗传学和病理生理学的理解,以及在诊断和治疗这种实体。本文对这些研究进展进行了总结。
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Espondiloartritis en la infancia

Juvenile-onset spondyloarthritis is a special group within the entities included in the concept of spondyloarthritis, and is characterized by a predominantly peripheral involvement (arthritis and enthesitis), and more frequent presentation as undifferentiated forms. However, like its adult-onset equivalent, it has the potential to develop structural damage and progress to juvenile ankylosing spondylitis, with consequent irreversible functional impairment. Many important advances have been made in the understanding of the genetics and pathophysiology of juvenile-onset spondyloarthritis, as well as in the diagnosis and treatment of this entity. These advances are summarized in this article.

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