在人类基因组富含gc的区域中存在老Alus -遗传算法的观点

S. J. Anastasoff
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引用次数: 0

摘要

超过10%的人类基因组是由一个被称为Alu重复序列的序列组成的,在我们的DNA中分布着超过100万份这种序列。对这个序列分布的详细分析表明,它以一种不寻常的方式分散。在这里提出的工作中,开发了一种遗传算法模拟作为建模转座子(其中Alu是一种类型)的基础。这个模拟被用来探索这种分布可能产生的进化条件。
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The presence of old Alus in GC-rich regions of the human genome - a genetic algorithm perspective
More than 10% of the human genome is comprised of a sequence known as an Alu repeat, with over a million copies of this distributed throughout our DNA. Detailed analysis of the distribution of this sequence shows it to be dispersed in an unusual way. In the work presented here, a genetic algorithm simulation was developed as the basis for modeling transposons (of which the Alu is one type). This simulation was used to explore the evolutionary conditions under which such a distribution could arise.
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