低出生体重儿标准化喂养方法的相关结果

Michelle Johnson
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引用次数: 0

摘要

标准化的喂养方法为低出生体重婴儿提供了许多有益的结果。具有统计学意义的坏死性小肠结肠炎(NEC)发病率降低的结果已经在多个研究中得到了重复。以营养为主要结局指标的研究发现,在肠外营养天数、从肠外和肠内营养中摄取能量和蛋白质的天数、开始饲喂后的0 / 10天以及实现完全肠内热量喂养的天数方面,均有统计学上显著的改善。与对照组相比,极低出生体重的婴儿达到120和160 mL/kg /天的速度明显更快,NEC的发病率也显著降低。其他以生长为主要结局指标的研究发现,恢复出生体重的天数明显缩短,体重<10百分位的婴儿出院的数量明显减少。对于月经后≤29周出生的婴儿,使用标准喂养方法导致体重明显增加。
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Outcomes Related to a Standardized Feeding Approach for Low Birth Weight Infants
A standardized approach to feeding offers numerous beneficial outcomes for low birth weight infants. Statistically significant outcomes for a decreased incidence of necrotizing enterocolitis (NEC) have been replicated across multiple studies. Studies with primary outcome measures of nutrition have found statistically significant improvements in days of parenteral nutrition, energy and protein intake from parenteral and enteral nutrition, days nil per os after feeds had been started, and days to achieve full enteral caloric feeds. Extremely low birth weight infants achieved 120 and 160 mL/kg per day significantly faster and with a significantly decreased incidence of NEC compared with controls. Additional studies with primary outcome measures of growth have found significantly lower days to return to birth weight, and significantly fewer infants discharged with weight <10th percentile. For infants born ≤29 weeks postmenstrual age, use of a standard approach to feeding resulted in significantly larger weigh...
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