气道是否有薄弱部位

Y. Shigeta
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引用次数: 1

摘要

目的:在我们前期的研究中,有报道称OSA的横断面气道呈三角形,尤其是肥胖患者。根据这一发现,我们假设在双侧后区存在气道结构性薄弱。在这篇简短的报告中,为了发现气道中的薄弱区域,我们观察了负压加载下气道的形态变化。方法:受试者为女性,年龄33岁,无阻塞性睡眠呼吸暂停。研究人员用压力计测量了她能稳定保持15秒的压力水平。在扫描CBCT (S_NP)期间施加该压力水平。在以下条件下,在15秒内通过CBCT扫描气道;呼吸正常,处于S_NP状态。测量鼻后棘水平至会厌尖端之间的气道容积。结果:正常呼吸时气道形态呈椭圆形。另一方面,S_NP下的气道呈三角形。正常呼吸时气道体积为16040mm3, S_NP下气道体积为6567mm3。与正常呼吸相比,S_NP下气道容积减少41%。结论:这篇简短的报告可以观察到负压下气道的形态。因此,气道可能被脂肪组织或负压从后外侧方向阻塞。这篇简短的报告提供了关于气道结构缺陷研究的重要性。
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Is there Weakness Area in Airway
Purpose: In our previous study, it was reported that the cross-section airway of OSA presented triangle shape, especially in the obese patients. From this finding, we hypothesized that there is structural weakness of airway in the bilateral posterior region. In this short report, to discover the weakness region in the airway, the airway configuration change under the negative pressure loading was observed. Methods: Subject was 33 year-old female, who had no OSA. It was investigated the pressure level of which she was able to keep same the same level stably and constantly for 15 seconds using a pressure gauge. This pressure level was applied during scanning CBCT (S_NP).The airway was scanned via a CBCT with 15 seconds, under following conditions; normal breathing and under S_NP. The airway volumes between the level of the posterior nasal spine and the tip of epiglottis were measured. Results: The airway configuration during normal breathing was elliptical shape. On the other hand, the airway under S_NP presented triangle shape. The airway volumes were 16040mm 3 during normal breathing, and 6567mm 3 under S_NP. The airway volume under S_NP decreased to 41%, compared with normal breathing. Conclusion: In this short report, it could observe the airway configuration under the negative pressure. As a result, the airway may be obstructed from posterolateral direction by fat tissue or negative pressure. This short report provided an importance of research regarding to the structural weakness in the airway.
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