Ontology algebra for composition of protein data sources

Most biological resources available today on the web provide a good number of cross-links to other resources with relevant information. However, in our opinion, what is still lacking is an integrated view that provides complete coverage of information through a single entry point. The main problem lies in interpreting biological nomenclature because the underlying data sources are inconsistent. In this paper we discuss Protein Ontology (PO) Algebra that we use for composition and interoperability of protein data sources. We outline the existing research in interoperability of biological data sources, before discussing our semantic interoperability approach in detail. The actual implementation of Protein Ontology is also discussed briefly in this paper, which depends on the strength of the Protein Ontology Algebra.