血清25-羟基维生素D水平作为变应性鼻炎的预测因素

Lia Restimulia, D. Munir
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引用次数: 0

摘要

引言:过敏与25-羟基维生素D缺乏有相关性。然而,确定血清25-羟基维生素D水平作为预测因素的研究数量有限,特别是在过敏性鼻炎(AR)中。这项研究从未在印度尼西亚实施,其主要目的是探讨这一主题。方法:采用连续抽样的方法招募15名受试者。采用电化学发光免疫分析法(ECLIA)定量测定血清25-羟基维生素D水平,通过列举所有鼻症状获得总鼻症状评分。对血清维生素D水平和TNSS数据进行统计学分析。结果:在我们前期研究的基础上,线性回归= 10,230 ~ 0,281(维生素D),呈负中相关(r = -0,613)。这一结果可以与维生素D水平为5.66 ng/mL的人相比较,可以预测鼻腔评分为8.64。结论:25-羟基维生素D可能是变应性鼻炎的预测因素,并呈负中相关。因此,在未来的研究需要实施。
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Serum 25-Hydroxyvitamin D Levels as a Predictive Factor for Allergic Rhinitis
Introduction: Allergy and 25-Hydroxyvitamin D deficiency were mentioned to be correlated. Still, there was limited number of studies in determining serum 25-Hydroxyvitamin D levels as a predictive factor, particularly in allergic rhinitis (AR). This study has never been implemented in Indonesia which the main objective was to explore this topic. Methods: Consecutive sampling was used in recruiting the fifteen subjects. Serum 25-Hydroxyvitamin D levels were quantified using electrochemiluminescence immunoassay (ECLIA) method while the total nasal symptom scores were acquired by enumerate all nasal symptoms. Data of serum vitamin D levels and TNSS were analysed statistically.Results: Based on our previous study, the predictive value was illustrated from linier regresion = 10,230 – 0,281 (vitamin D), with negative moderate correlation (r = -0,613). This result can be comparable for someone with vitamin D level of 5.66 ng/mL that could predicted as 8.64 nasal score. Conclusion: 25-Hydroxyvitamin D could be a predictive factor for allergic rhinitis with negative moderate correlation. Hence, in the future research needs to be implemented.
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