High-throughput cell-patterning with a self-assembled bubble-raft

This study fabricated patterned cell culture system with a self-assembled bubble-raft created on a general cell-culture medium. The bubble raft was composed of bubbles generated by bubbling. After cells were seeded on the bubble raft, the cells were trapped in a gap between adjacent bubbles. The pattern of adherent cells were obtained within 2 h after the cell seeding.