Sono和光刺激的氯E6纳米复合材料在荷瘤小鼠中的作用:即将到来的癌症治疗

Ammar Yahya Kadhim Almamoori, G. H. A. Elsamie, M. Metwally, Samir Ali
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引用次数: 2

摘要

本研究旨在研究活化氯E6纳米复合材料(Nano-CE6)在癌症靶向治疗中的有效性。本研究以雄性瑞士白化小鼠为研究对象,将植入埃利希瘤(Ehrlich tumor, EAC)的小鼠分为6组。使用了两种能源;激光和超声波。结果表明,纳米ce6是光动力或声动力治疗肿瘤的潜在增敏剂。纳米ce6在抑制肿瘤生长和诱导细胞死亡方面发挥着重要作用。红外激光和超声活化纳米ce6具有潜在的抗肿瘤作用。结果表明,(FA-NGO-CE6)可以作为一种独特的纳米复合材料用于癌症靶向治疗SPDT。
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Sono and photo stimulated Chlorine E6 nanocomposite in tumor-bearing mice: upcoming cancer treatment
This study was directed at study the effectiveness of cancer targeted therapy using the activated Chlorine E6 nanocomposite (Nano-CE6). Study was applied on male Swiss albino mice, implanted with Ehrlich tumor (EAC) divided into six groups. Two energy sources were used; laser and Ultrasound. Results showed that Nano-CE6 is a potential sensitizer for photodynamic or sonodynamic treatment of tumor. Nano-CE6 plays an important role in tumor growth inhibition and cell death induction. Activated Nano-CE6 with both infrared laser and ultrasound has a potential antitumor effect. The results indicated that (FA–NGO–CE6) could be used as a unique nanocomposite for cancer targeted therapy SPDT.
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