ParaKavosh:寻找生物网络基序的并行算法

Z. Kashani, A. Masoudi-Nejad, A. Nowzari-Dalini
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引用次数: 0

摘要

生物网络最近在寻找它们的基序方面受到了极大的关注。motif可以被认为是出现在特定网络中的子图,其频率明显高于随机网络。这一问题的重要性引起了人们对现有算法改进的关注。由于算法的运行时间是一个重要的方面,因此应用并行技术可以更好地改进算法。本文提出了一种寻找网络基元的并行算法(ParaKavosh)。我们的算法在大肠杆菌、酿酒葡萄球菌、智人和褐家鼠网络上进行了测试。用一种高效的顺序算法对得到的结果进行分析,证明了该算法的代价最优性。结果表明,该算法在运行时间上有较好的表现。
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ParaKavosh: A Parallel Algorithm for Finding Biological Network Motifs
Biological networks have recently gathered much attraction in finding their motifs. Motifs can be considered as subgraphs that occur in a particular network at significantly higher frequencies than random networks. The importance of this problem causes attention of improving the existing algorithms. As the runtime of an algorithm is an important aspect, applying parallel techniques is appropriate for better improvement. In this paper a parallel algorithm (ParaKavosh) for finding network motifs is presented. Our algorithm is tested on E. coli, S. cerevisiae, Homo sapiens and Rattus norvegicus networks. The cost optimality of the algorithm is also shown by analyzing the obtained results with an efficient sequential algorithm. The results show that the algorithm performs much better in terms of runtime.
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