{"title":"微反应器PCR芯片阵列及其控制系统","authors":"Xianming Li, Haifa Liu","doi":"10.1109/ICAL.2009.5262598","DOIUrl":null,"url":null,"abstract":"A kind of low cost micro-reactor polymerase chain reaction (PCR) chips is designed in which there are no temperature sensor and heater, and a temperature control system to the array of this kind of chips is developed. The control system is composed of a unitized macroscopic control subsystem and a distributed microcosmic control subsystem. The temperature that PCR chips need is controlled approximately by unitized macroscopic subsystem in which water as heat medium is pumped through a special heat exchanger. An array of miniature heaters corresponding to the array of PCR chips is made in a flexible printed circuit board that provides temperature compensation to every PCR chip. To be composed a cascade control system and using statistical quality control(SPC) method, the temperature of every chip is controlled quickly and accurately by the miniature heaters cooperating together with the heat exchanger.","PeriodicalId":140270,"journal":{"name":"2009 IEEE International Conference on Automation and Logistics","volume":"9 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2009-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"The array of micro-reactor PCR chips and its control system\",\"authors\":\"Xianming Li, Haifa Liu\",\"doi\":\"10.1109/ICAL.2009.5262598\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"A kind of low cost micro-reactor polymerase chain reaction (PCR) chips is designed in which there are no temperature sensor and heater, and a temperature control system to the array of this kind of chips is developed. The control system is composed of a unitized macroscopic control subsystem and a distributed microcosmic control subsystem. The temperature that PCR chips need is controlled approximately by unitized macroscopic subsystem in which water as heat medium is pumped through a special heat exchanger. An array of miniature heaters corresponding to the array of PCR chips is made in a flexible printed circuit board that provides temperature compensation to every PCR chip. To be composed a cascade control system and using statistical quality control(SPC) method, the temperature of every chip is controlled quickly and accurately by the miniature heaters cooperating together with the heat exchanger.\",\"PeriodicalId\":140270,\"journal\":{\"name\":\"2009 IEEE International Conference on Automation and Logistics\",\"volume\":\"9 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2009-09-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"2009 IEEE International Conference on Automation and Logistics\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/ICAL.2009.5262598\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"2009 IEEE International Conference on Automation and Logistics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/ICAL.2009.5262598","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
The array of micro-reactor PCR chips and its control system
A kind of low cost micro-reactor polymerase chain reaction (PCR) chips is designed in which there are no temperature sensor and heater, and a temperature control system to the array of this kind of chips is developed. The control system is composed of a unitized macroscopic control subsystem and a distributed microcosmic control subsystem. The temperature that PCR chips need is controlled approximately by unitized macroscopic subsystem in which water as heat medium is pumped through a special heat exchanger. An array of miniature heaters corresponding to the array of PCR chips is made in a flexible printed circuit board that provides temperature compensation to every PCR chip. To be composed a cascade control system and using statistical quality control(SPC) method, the temperature of every chip is controlled quickly and accurately by the miniature heaters cooperating together with the heat exchanger.